Pricey Nuvigil competes with coffee—and has a lot more side effects

"Roger Greer, a 45-year-old water treatment plant worker from Coatesville, Pa., was surfing the Internet when he discovered that his constant fatigue had a medical name: shift work sleep disorder. The starting time of Greer’s job rotates weekly, leaving him sleepy on the job and ornery at home. The website had an ad suggesting he ask his doctor if an alertness pill made by Cephalon (CEPH), called Nuvigil, is right for him. A year later, “I don’t have those sleepy moments,” says Greer. “Now at 3 in the morning, the absolute worst time for anybody, I no longer have the fear of missing something here at work.”

Workers like Greer are prime targets for a Cephalon marketing campaign—on the Internet and radio, in doctors’ offices, and at community meetings—that aims to educate America’s 15 million shift workers about the disorder. For the drugmaker, it’s a way to build brand recognition and sales for Nuvigil, a newer version of its blockbuster narcolepsy drug, Provigil, which loses patent protection next year. But the campaign has sparked concern by some doctors about whether a pharmaceutical solution is the best way to stay alert on the job. Nuvigil hasn’t been proved more effective than coffee, is classified as possibly addictive, and carries side effects that can be fatal, according to the drug’s label."

The per-pill cost of Nuvigil is six times the cost of a medium Starbucks coffee D. Hurst/Alamy

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As stated in the body of the Bloomberg Article, Nuvigil is a new version of a narcolepsy drug, Provigil, which loses patent protection next year. So we can see why there is a big push to find a new and bigger audience for this drug. Make no mistake, shift work is life shortening because of its effect on sleep cycles. But does the risk/reward of Nuvigil make sense?

Dr David Marcon
Work Smarter Not Harder!
Cincinnati, Ohio
wwww.drdavidmarcon.com