"The hormone leptin acts as an appetite suppressor. Some people see Obesity as being a result of leptin resistance - the body no longer reacts to leptin.....appetite is no longer suppressed. So this study suggests that sprinting kicks off the same cascade of signals as does leptin. It signals you to stop eating.... "
In conclusion, this study shows that most of the signaling pathways activated by leptin in rodent skeletal muscle are also activated by sprint exercise in human skeletal muscle, despite a small reduction of leptin serum concentration after the sprint exercise. These findings imply that sprint exercise behave as a leptin mimetic and could be used to stimulate the leptin signaling pathways in human skeletal muscle. This opens the possibility of using sprint exercise to circumvent leptin resistance in obese humans and may lead to increased leptin sensitivity. We provide some evidence to support that the effects of sprint exercise on ERK, STAT3, STAT5, and SOCS3 are not mediated by changes in either serum leptin or IL-6 concentrations, while the expression of SOCS3 and the phosphorylation of STAT5 may have been induced by GH. Importantly, we showed that glucose ingestion 1 h prior to the sprint exercise abolishes or delays some of the exercise-elicited signaling responses, implying that the adaptative responses to sprint exercise training may be modulated by the postabsorp- tive state.
Read more...
I have not digested the whole study as of yet, but if sprinting is effective in triggering leptin the door is open for research on humans using any type of high intensity, short duration activity/exercise. Of course this feeds into the idealogy of OUR TRAINING REGIME!
Dr David Marcon
Work Smarter Not Harder!
Cincinnati, Ohio
www.drdaavidmarcon.com
No comments:
Post a Comment